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The restriction of calories will improve mitochondrial functions, leading to reduced ROS production and increased energy output

Thus, ACs play a critical role in mitochondrial energy metabolism, essential for functioning of all tissues, as they transport long-chain fatty acids into mitochondria for -oxidation, a key energy production process [13]

This additional acetyl group allows L-carnitine to cross the blood-brain barrier, a natural barrier between the bloodstream and the central nervous system

Relative gene expression was determined by CT

[10] Imbe, A., Tanimoto, K., Inaba, Y., Sakai, S., Shishikura, K., Imbe, H.,

doi: 10.3390/antiox12051042 71